Botox injections are being used for chronic pain as well as for wrinkle
reduction and prevention. Migraine headaches and other chronic pain conditions
are responding well to Botox injections. The primary objective of migraine
prophylaxis is to reduce the duration, frequency, and severity of migraine
attacks. For this reason, Botox injections have become a standard treatment
in pain management.
A migraine headache is a common disabling condition, and its lifetime prevalence
is around 15%. This condition will limit daily activities, affect the
quality of life, and become a chronic issue. When migraine headaches progress
from an episodic migraine to a chronic migraine, the prevalence rate is
around 2% of the general population. Botox injections offer an alternative
therapy for people who suffer from these headaches.
Causes of a Chronic Migraine
The understanding of a chronic migraine has improved with research over
the last 20 years. It is likely that many factors are involved with migraine
headaches. The widely accepted theory for a migraine suggests that cortical
spreading depression, which involves nerve hyperactivity, followed by
an area cortical depression, accounts for the aura. In addition, the headache
depends on activation of a certain nerve-vascular pain pathway.
Other factors that contribute to migraines include central and peripheral
sensitization, neurogenic inflammation, and cortical hyperexcitability.
In addition, pain-induced functional activation of certain brain regions,
and atypical pain modulation plays a role in transforming episodic migraines
into chronic migraines. Another major factor in this process is cortical
Botox Injection Side Effects
Botulinum neurotoxins are produced by
Clostridium botulinum strains. Botox works by causes muscle paralysis. When muscles are relaxed,
no wrinkles can occur. In addition, pain decreases because Botox affects
acetylcholine release from nerves. This substance has an effect that is
dependent on neurotransmitter release from certain neurons of the muscle fibers.
Botox has side effects, but they are rare. These include dizziness, difficulty
swallowing, muscle weakness, nausea, flu-like pain, swollen and/or droopy
eyelid, eye irritation, reduced blinking, sensitivity to light, and tearing.
When used for migraine prevention, neck pain may occur. If any of these
side effects occur, please notify your physician.
Botox Injection Before and After Results
The effects of Botox for migraines has been observed many times by plastic
surgeons who were treating patients for wrinkles. In recent research studies,
50% of patients had complete remission of headaches, while other clinical
studies showed that the duration of effectiveness was around 4 months.
Botulinum toxin A treatment has also been shown to reduce the number of
headaches per month, lower the severity of the pain, and reduce the number
of medications used.
In a recent study, Botox was used for chronic daily headache. Researchers
found that this medication was found to be quite effective, with the majority
of patients reporting fewer headache days. In a large randomized, double-blind
trial, Botox had an 80% success rate when used to treat headaches. Another
study showed botulinum toxin A to be significantly superior to placebo
for migraine prevention.